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Chantix




Chantix ( varenicline tartrate) was developed by Pfizer, Inc. as a drug that was specifically to aid in smoking cessation. It differs from other quit smoking drugs and nicotine replacement therapies in that it is a nicotine receptor partial agonist and has a two-fold method of working.

Varenicline tartrate not only reduces the cravings for nicotine by binding with the nicotine receptors in the brain but also decreases the pleasurable effects derived from cigarettes.


Side effects of Chantix

Some of the more common side effects include:
  • Nausea,
  • vomiting,
  • constipation,
  • trouble sleeping,
  • unusual dreams,
  • flatulence (gas),
  • changes in taste.

More serious side effects of varenicline tartrate(and the ones that are getting more of the press) are:
  • depressed mood,
  • thoughts of suicide,
  • attempted suicide
  • changes in behavior – such as hostility or aggression
  • heart rhythm disturbances,
    • heart attacks,
  • seizures and
  • diabetes.

The side effects are such that the FDA as of July, 2009 now requires Pfizer to place a black box warning on the package insert. A black box warning means that medical studies indicate that the drug carries a significant risk of serious or even life-threatening adverse effects.

Furthermore the Federal Aviation Administration now prohibits pilots and air traffic controllers from using varenicline tartrate. Truckers are also banned from its use.


The Cost

Varenicline tartrate ranges around $3-$4 a tablet and may or may not be covered by insurance. Its makers recommend that the user stay continue its use for 12 weeks. If after 12 weeks the person is still not smoking, then it is advised that the person continue for another 12 weeks. This would bring the cost for the full course of treatment to over $670.

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